By Leonard Gomella, Steven Haist, Aimee Adams

Must-know information regarding one thousand of the main widespread medictions -- at your fingertips and able to use! compliment for a prior version: "This is a truly beneficial and updated pocket reference for standard drugs. five Stars!"--Doody's overview provider Why spend time plowing via details you do not need while what you actually need to grasp is correct the following in a single concise advisor? sufficiently small to slot in a lab coat or blouse pocket, Clinician's Pocket Drug Reference is simply what you want to perform more secure and quicker medication. prepared alphabetically by way of frequent drug identify universal makes use of, mechanisms of motion, dosages (adult and pediatric), precautions/contraindications, shape provided, and notes/common negative effects features a record of the medicinal drugs geared up by way of drug type Summaries of the FDA “black field” precautions and contraindications up to date to incorporate assurance of greater than 24 new medications and the elimination of gear taken off the industry

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Topical: Initial herpes genitalis: Apply q3h (6×/d) for 7 d. HSV encephalitis: 10 mg/kg IV q8h ¥ 10 d. Herpes zoster: 800 mg PO 5×/d for 7–10 d. IV: 5–10 mg/kg/dose IV q8h. Peds. Genital HSV: 3 mo–2 y: 15 mg/kg/d IV ÷ q8h × 5–7 d, 60 mg/kg/d max. 2–12 y: 1200 mg/d PO ÷ q8h × 7–10 d. >12 y: 1000–1200 mg PO ÷ q8h × 7–10 d. HSV encephalitis: 3 mo–2 12 y: 60 mg/kg/d IV ÷ q8h × 10 d. >12 y: 30 mg/kg/d IV ÷ q8h × 10 d. Chickenpox: ≥2 y: 20 mg/kg/dose PO qid × 5 d. Shingles: <12 y: 30 mg/kg/d PO or 1500 mg/ m2/d IV ÷ q8h × 7–10 d; ↓ w/ CrCl <50 mL/min Caution: [B, +] CI: Hypersensitivity to compound Disp: Caps 200 mg; tabs 400, 800 mg; susp 200 mg/5 mL; Inj 500 & 1000 mg/vial; Inj soln 25 mg/mL, 50 mg/mL oint 5% and cream 5% SE: Dizziness, lethargy, malaise, confusion, rash, IV site inflammation; transient ↑ Cr/BUN Notes: PO better than topical for herpes genitalis Adalimumab (Humira) WARNING: Cases of TB have been observed; ✓ TB skin test prior to use; Hep B reactivation possible, invasive fungal and other opportunistic Infxns reported; malignancies in children and young adults reported Uses: *Mod–severe RA w/ an inadequate response to one or more DMARDs, psoriatic arthritis (PA), juvenile idiopathic arthritis (JIA), plaque psoriasis, ankylosing spondylitis (AS), Crohn Dz* Action: TNF-α inhibitor Dose: RA, PA, AS: 40 mg SQ qOwk; may ↑ 40 mg qwk if not on MTX.

Metabolic alkalosis 250 mg IV q6h × 4 or 500 mg IV × 1 Peds. Epilepsy: 8–30 mg/kg/24 h PO in ÷ doses; max 1 g/d. Diuretic: 5 mg/kg/24 h PO or IV. Alkalinization of urine: 5 mg/kg/dose PO bid-tid. ] CI: Perforated tympanic membranes Disp: 2% otic soln SE: Local irritation Acetylcysteine (Acetadote, Mucomyst) Uses: *Mucolytic, antidote to APAP hepatotox/OD* adjuvant Rx chronic bronchopulmonary Dzs & CF* prevent contrast-induced renal dysfunction Action: Splits mucoprotein disulfide linkages; restores glutathione in APAP OD to protect liver Dose: Adults & Peds.

12 y: 30 mg/kg/d IV ÷ q8h × 10 d. Chickenpox: ≥2 y: 20 mg/kg/dose PO qid × 5 d. Shingles: <12 y: 30 mg/kg/d PO or 1500 mg/ m2/d IV ÷ q8h × 7–10 d; ↓ w/ CrCl <50 mL/min Caution: [B, +] CI: Hypersensitivity to compound Disp: Caps 200 mg; tabs 400, 800 mg; susp 200 mg/5 mL; Inj 500 & 1000 mg/vial; Inj soln 25 mg/mL, 50 mg/mL oint 5% and cream 5% SE: Dizziness, lethargy, malaise, confusion, rash, IV site inflammation; transient ↑ Cr/BUN Notes: PO better than topical for herpes genitalis Adalimumab (Humira) WARNING: Cases of TB have been observed; ✓ TB skin test prior to use; Hep B reactivation possible, invasive fungal and other opportunistic Infxns reported; malignancies in children and young adults reported Uses: *Mod–severe RA w/ an inadequate response to one or more DMARDs, psoriatic arthritis (PA), juvenile idiopathic arthritis (JIA), plaque psoriasis, ankylosing spondylitis (AS), Crohn Dz* Action: TNF-α inhibitor Dose: RA, PA, AS: 40 mg SQ qOwk; may ↑ 40 mg qwk if not on MTX.

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